Photocatalytic Continuous-Flow Methods for C-H Functionalization

Photocatalysis enables direct C-H bond functionalization but requires efficient irradiation, which is challenging with traditional batch techniques. Continuous flow chemistry, with its small reactor dimensions, ensures efficient irradiation, leading to reduced reaction times and higher selectivities. This technology allows precise control over reaction conditions, enhances reproducibility, and facilitates the use of gaseous reagents by increasing their solubility under higher pressures. This article explores the benefits and applications of flow chemistry for photocatalytic C-H functionalization.