We aim to provide solutions for challenging chemical problems and to realize sustainable, robust photocatalytic transformations.

The research in our group is driven by curiosity and the understanding of photophysical properties of photocatalysts as well as reaction mechanisms. A key aspect of our research philosophy is to learn from other areas such as materials sciences.

publications since 2010

projects in Austria & international

2024

A photoactive nickel complex provides evidence for a general Ni (I)/Ni(III) paradigm in cross-coupling catalysis

L. Anghileri, H. Baunis, A. R. Bena, C. Giannoudis, J. H. Burke, S. Reischauer, C. Merschjann, R. F. Wallik, G. Simionato, S. Kovalenko, L. Dell’Amico, R. M. van der Veen, B. Pieber

ChemRxiv 2024, DOI: 10.26434/chemrxiv-2024-896n0
2023

Formal Radical Deoxyfluorination of Oxalate‐Activated Alcohols Triggered by the Selectfluor‐DMAP Charge‐Transfer Complex

H. Baunis, B. Pieber

Eur. J. Org. Chem. 2023, 26, e202300769

Photocatalytic Cleavage of Trityl Protected Thiols and Alcohols

S. Murakami, C. Brudy, M. Bachmann, Y. Takemoto, B. Pieber

Synthesis 2023, 55, 1367-1374

Programmable Photocatalytic Activity of Multicomponent Covalent Organic Frameworks Used as Metallaphotocatalysts

M. Traxler, S. Reischauer, S. Vogl, J. Roeser, J. Rabeah, C. Penschke, P. Saalfrank, B. Pieber, A. Thomas

Chem. Eur. J. 2022, 29, e202202967

Visible-light-mediated Oxidative Debenzylation of 3-O-Benzyl-1, 2:5,6-d-O-isopropylidene-α-D-glucofuranose

A. Madani, E. T. Sletten, C. Cavedon, P. H. Seeberger, B. Pieber

Org. Synth. 2023, 100, 271-286

Special Collection: Photocatalytic Synthesis

L. Næsborg, B. Pieber, O. S. Wenger

ChemCatChem, 2023, 15, e202300683

In situ Reaction Monitoring in Photocatalytic Organic Synthesis

A. Madani, B. Pieber

ChemCatChem, 2023 15, e202201583

Catalytic Properties of High Nitrogen Content Carbonaceous Materials

E. Lepre, S. Rat, C. Cavedon, P. H. Seeberger, B. Pieber, M. Antonietti, N. López‐Salas

Angew. Chem. Int. Ed. 2023, 62, e202211663
2022

Photocatalytic Continuous-Flow Methods for C-H Functionalization

B. Pieber

Handbook of CH‐Functionalization (Ed. D. Maiti) 2022, https://doi.org/10.1002/9783527834242.chf0152

Modulating the Surface and Photophysical Properties of Carbon Dots to Access Colloidal Photocatalysts for Cross-Couplings

Z. Zhao, B. Pieber, M. Delbianco

ACS Catal. 2022, 12, 13831-13837

Benzylic Fluorination Induced by a Charge-Transfer Complex with a Solvent-Dependent Selectivity Switch

A. Madani, L. Anghileri, M. Heydenreich, H. M. Möller, B. Pieber

Org. Lett. 2022, 24, 5376-5380

tert‐Butyl Nitrite (First Update)

E. T. Sletten, P. H. Seeberger, B. Pieber

e-EROS, 2022, https://doi.org/10.1002/047084289X.rn01922.pub2

Intraligand Charge Transfer Enables Visible-Light-Mediated Nickel-Catalyzed Cross-Coupling Reactions

C. Cavedon, S. Gisbertz, S. Reischauer, S. Vogl, E. Sperlich, J. H. Burke, R. F. Wallick, S. Schrottke, W.-H. Hsu, L. Anghileri, Y. Pfeifer, N. Richter, C. Teutloff, H. Müller‐Werkmeister, D. Cambié, P. H. Seeberger, J. Vura‐Weis, R. M. van der Veen, A. Thomas, B. Pieber

Angew. Chem. Int. Ed. 2022, 61, e202211433

Heterogeneous metallaphotoredox catalysis in a continuous-flow packed-bed reactor

W.-H. Hsu, S. Reischauer, P. H. Seeberger, B. Pieber, D. Cambié

Beilstein J. Org. Chem. 2022, 18, 1123-1130

Acridine‐Functionalized Covalent Organic Frameworks (COFs) as Photocatalysts for Metallaphotocatalytic C−N Cross‐Coupling

M. Traxler, S. Gisbertz, P. Pachfule, J. Schmidt, J. Roeser, S. Reischauer, J. Rabeah, B. Pieber, A. Thomas

Angew. Chem. Int. Ed. 2022, 61, e202117738
2021

Recyclable, Bifunctional Metallaphotocatalysts for C− S Cross‐Coupling Reactions

S. Reischauer, B. Pieber

ChemPhotoChem 2021, 5, 716-720

Emerging concepts in photocatalytic organic synthesis

S. Reischauer, B. Pieber

iScience 2021, 24, 102209

Carbon dot/TiO2 nanocomposites as photocatalysts for metallaphotocatalytic carbon–heteroatom cross-couplings

Z. Zhao, S. Reischauer, B. Pieber, M. Delbianco

Green Chem. 2021, 23, 4524-4530

Chromoselective Photocatalysis Enables Stereocomplementary Biocatalytic Pathways

L. Schmermund, S. Reischauer, S. Bierbaumer, C. K. Winkler, A. Diaz‐Rodriguez, L. J. Edwards, S. Kara, T. Mielke, J. Cartwright, G. Grogan, B. Pieber, W. Kroutil

Angew. Chem. Int. Ed. 2021, 60, 6965-6969

Visible-Light-Mediated Oxidative Debenzylation Enables the Use of Benzyl Ethers as Temporary Protecting Groups

C. Cavedon, E. T. Sletten, A. Madani, O. Niemeyer, P. H. Seeberger, B. Pieber

Org. Lett. 2021, 23, 514-518
2020

Modular, Self-Assembling Metallaphotocatalyst for Cross-Couplings Using the Full Visible-Light Spectrum

S. Reischauer, V. Strauss, B. Pieber

ACS Catal. 2020, 10, 13269-13274

Heterogeneous Photocatalysis in Organic Synthesis

S. Gisbertz, B. Pieber

ChemPhotoChem 2020, 4, 456-475

Photochemical Strategies for Carbon–Heteroatom Bond Formation

C. Cavedon, P. H. Seeberger, B. Pieber

Eur. J. Org. Chem. 2020, 1379-1392

An oscillatory plug flow photoreactor facilitates semi-heterogeneous dual nickel/carbon nitride photocatalytic C–N couplings

C. Rosso, S. Gisbertz, J. D. Williams, H. P. L. Gemoets, W. Debrouwer, B. Pieber, C. O. Kappe

React. Chem. Eng. 2020, 5, 597-604

Overcoming limitations in dual photoredox/nickel-catalysed C–N cross-couplings due to catalyst deactivation

S. Gisbertz, S. Reischauer, B. Pieber

Nat. Catal. 2020, 3, 611-620

Evidence for Photocatalyst Involvement in Oxidative Additions of Nickel-Catalyzed Carboxylate O-Arylations

J. A. Malik, A. Madani, B. Pieber, P. H. Seeberger

J. Am. Chem. Soc. 2020, 142, 11042-11049

Dichloromethylation of enones by carbon nitride photocatalysis

S. Mazzanti, B. Kurpil, B. Pieber, M. Antonietti, A. Savateev

Nat. Commun. 220, 11, 1387
2019

Safe and Scalable Continuous Flow Azidophenylselenylation of Galactal to Prepare Galactosamine Building Blocks

M. Guberman, B. Pieber, P. H. Seeberger

Org. Process Res. Dev. 2019, 23, 2764-2770

Semiheterogeneous Dual Nickel/Photocatalytic (Thio)etherification Using Carbon Nitrides

C. Cavedon, A. Madani, P. H. Seeberger, B. Pieber

Org. Lett. 2019, 21, 5331-5334

Semi‐heterogeneous Dual Nickel/Photocatalysis using Carbon Nitrides: Esterification of Carboxylic Acids with Aryl Halides

B. Pieber, J. A. Malik, C. Cavedon, S. Gisbertz, A. Savateev, D. Cruz, T. Heil, G. Zhang, P. H. Seeberger

Angew. Chem. Int. Ed. 2019, 58, 9575-9580
2018

Continuous Heterogeneous Photocatalysis in Serial Micro-Batch Reactors

B. Pieber, M. Shalom, M. Antonietti, P. H. Seeberger, K. Gilmore

Angew. Chem. Int. Ed. 2018, 57, 9976-9979
2017

The Hitchhiker’s Guide to Flow Chemistry

M. B. Plutschack, B. Pieber, K. Gilmore, P. H. Seeberger

Chem. Rev. 2017, 117, 11796-11893

Integrated Flow Processing — Challenges in Continuous Multistep Synthesis

B. Pieber, K. Gilmore, P. H. Seeberger

J. Flow Chem. 2017, 7, 129-136
2016

Taming" forbidden" olefin reductions using hydrazine and oxygen by continuous flow technology

B. Pieber, C. O. Kappe

Chim. Oggi/Chem. Today 2016, 34, 38-42

Selective Olefin Reduction in Thebaine Using Hydrazine Hydrate and O2 under Intensified Continuous Flow Conditions

B. Pieber, D. P. Cox, C. O. Kappe

Org. Process Res. Dev. 2016, 20, 376-385

Continuous Synthesis of Hydantoins: Intensifying the Bucherer–Bergs Reaction

J. L. Monteiro, B. Pieber, A. G. Corrêa, C. O. Kappe

Synlett, 2016, 27, 83-87

Generation and Synthetic Application of Trifluoromethyl Diazomethane Utilizing Continuous Flow Technologies

B. Pieber, C. O. Kappe

Org. Lett. 2016, 18, 1076-1079

Aerobic Oxidations in Continuous Flow

B. Pieber, C. O. Kappe

Top. Organomet. Chem. 2016, 57, 97-136
2015

A Sequential Ugi Multicomponent/Cu-Catalyzed Azide–Alkyne Cycloaddition Approach for the Continuous Flow Generation of Cyclic Peptoids

C. E. M. Salvador, B. Pieber, P. M. Neu, A. Torvisco, C. K. Z. Andrade, C. O. Kappe

J. Org. Chem. 2015, 80, 4590-4602

Continuous Flow Reduction of Artemisinic Acid Utilizing Multi‐Injection Strategies—Closing the Gap Towards a Fully Continuous Synthesis of Antimalarial Drugs

B. Pieber, T. Glasnov, C. O. Kappe

Chem. Eur. J. 2015, 21, 4368-4376
2014

Immobilized Iron Oxide Nanoparticles as Stable and Reusable Catalysts for Hydrazine‐Mediated Nitro Reductions in Continuous Flow

M. M. Moghaddam, B. Pieber, T. Glasnov, C. O. Kappe

ChemSusChem 2014, 7, 3122-3131

Flash carboxylation: fast lithiation–carboxylation sequence at room temperature in continuous flow

B. Pieber, T. Glasnov, C. O. Kappe

RSC Adv. 2014, 4, 13430-13433

Regulation of Gene Expression through a Transcriptional Repressor that Senses Acyl-Chain Length in Membrane Phospholipids

H. F. Hofbauer, F. H. Schopf, H. Schleifer, O. L. Knittelfelder, B. Pieber, G. N. Rechberger, H. Wolinski, M. L. Gaspar, C. O. Kappe, J. Stadlmann, K. Mechtler, A. Zenz, K. Lohner, O. Tehlivets, S. A. Henry, S. D. Kohlwein

Dev. Cell 2014, 29, 729-739
2013

In Situ Generation of Diimide from Hydrazine and Oxygen: Continuous-Flow Transfer Hydrogenation of Olefins

B. Pieber, S. T. Martinez, D. Cantillo, C. O. Kappe

Angew. Chem. Int. Ed. 2013, 52, 10241-10244

Direct aerobic oxidation of 2-benzylpyridines in a gas–liquid continuous-flow regime using propylene carbonate as a solvent

B. Pieber, C. O. Kappe

Green Chem. 2013, 15, 320-324

Microwave Effects in Organic Synthesis: Myth or Reality?

C. O. Kappe, B. Pieber, D. Dallinger

Angew. Chem. Int. Ed. 2013, 52, 1088-1094
2012

Direct Arylation of Benzene with Aryl Bromides using High‐Temperature/High‐Pressure Process Windows: Expanding the Scope of C–H Activation Chemistry

B. Pieber, D. Cantillo, C. O. Kappe

Chem. Eur. J. 2012, 18, 5047-5055

Copper-Catalyzed Formation of C–O Bonds by Direct α-C–H Bond Activation of Ethers Using Stoichiometric Amounts of Peroxide in Batch and Continuous-Flow Formats

G. S. Kumar, B. Pieber, K R. Reddy, C. O. Kappe

Chem. Eur. J. 2012, 18, 6124-6128
2010

Novel sensitive determination of steryl glycosides in biodiesel by gas chromatography–mass spectroscopy

B. Pieber, S. Schober, C. Goebl, M. Mittelbach

J. Chrom. A 2010, 1217, 6555–6561